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The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias
(Frontiers Media, 2016)
The capacity of the nervous system to generate neuronal networks relies on the establishment and maintenance of synaptic contacts. Synapses are composed of functionally different presynaptic and postsynaptic compartments. ...
Drosophila Atlastin in motor neurons is required for locomotion and presynaptic function
(Company of Biologists Ltd., 2017)
Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...
Microtubule-associated protein 1B ( MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology (vol 6, 30069, 2016).
(CIENCIAS, 2016)
Microtubule-associated protein 1B (MAP1B) is expressed predominantly during the early stages of development of the nervous system, where it regulates processes such as axonal guidance and elongation. Nevertheless, MAP1B ...
Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology
(Nature Publishing Group, 2016)
Microtubule-associated protein 1B (MAP1B) is expressed predominantly during the early stages of development of the nervous system, where it regulates processes such as axonal guidance and elongation. Nevertheless, MAP1B ...
Nerve fibres: a possible role in keloid pathogenesis
(Blackwell Publishing, 2008-03-01)
Synaptic transmission block by presynaptic injection of oligomeric amyloid beta
(NATL ACAD SCIENCES, 2009)
Early Alzheimer`s disease (AD) pathophysiology is characterized by synaptic changes induced by degradation products of amyloid precursor protein (APP). The exact mechanisms of such modulation are unknown. Here, we report ...
The neuromuscular activity of paradoxin: A presynaptic neurotoxin from the venom of the inland taipan (Oxyuranus microlepidotus)
(Pergamon-elsevier Science LtdOxfordInglaterra, 2007)